Biography
Tammy (Tamsyn) graduated with a Bachelor of Science in Physiology with 1st class honours (2011) and a Bachelor of Medicine and Surgery with Merit from the University of Bristol (2014). She received the Physiological Society (UK) Undergraduate Prize for highest mark in written finals, and for her research project investigating alternative splicing as a novel therapeutic target for ocular neovascularisation, supervised by Professor David Bates.
Tammy began her clinical career with an Academic Foundation Programme in Trauma and Orthopaedics in the West Midlands (2014-16), before coming to Oxford to take up an NIHR Academic Clinical Fellowship in General Surgery (2016-18). She completed her Core Surgical Training, a PGDip in Health Research and was awarded a Cancer Research UK Clinical Research Training Fellowship (2018-22) to support her DPhil.
Research Interests
- Normothermic machine perfusion
- Translational pharmacokinetics
- Isolated Normothermic Liver Chemoperfusion (INLiC)
- Enhanced drug delivery to liver tumours
Current Projects
Normothermic machine perfused organs to model pharmacokinetics:
Use of ex vivo, porcine and human, normothermic perfused liver, kidney and spleen to predict human pharmacokinetics.
Isolated Normothermic Liver Chemoperfusion (INLiC):
Preclinical safety and feasibility of delivering high dose cancer therapeutics to the vascularly-isolated, perfused liver in a large animal model
